Abstract Valproic acid (VPA) exposure as an environmental factor that confers risk of autism spectrum disorder (ASD), its functional mechanisms in the human brain remain unclear since relevant studies are currently restricted to two-dimensional cell cultures and animal models.To identify mechanisms by which VPA contribute to ASD risk in human, here
Abstract Background Machine Learning (ML) plays a crucial role in biomedical research.Nevertheless, it still has limitations in data integration and irreproducibility.To address these challenges, robust methods are needed.Pancreatic ductal adenocarcinoma (PDAC), a highly aggressive cancer with low early detection rates and survival rates, is used a
Innovation is becoming more and more participatory.Discourses insisting on the desirable involvement of users and lay citizens in innovation-making processes are burgeoning around the globe.This burgeoning is often fostered and supported by innovation scholars whose studies on, and calls for more open and participatory forms of innovation have rece
Rhoptries are specialized secretory organelles conserved across the Apicomplexa phylum, essential for host cell invasion and critical for subverting KERA 3 MASK of host cellular and immune functions.They contain proteins and membranous materials injected directly into the host cells, participating in parasitophorous vacuole formation.Toxoplasma gon
OBJECTIVE The objective of this study was to determine the frequency of dural tear in patients with depressed skull fractures.MATERIAL and Method This cross-sectional study was conducted in department of Neurosurgery Pakistan institute of Medical Sciences Islamabad from January 2010 to December 2011.All patients of either gender with depressed skul